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Arch Iran Med. 2019;22(12): 733-735.
PMID: 31823627
Scopus ID: 85076146819
  Abstract View: 1246
  PDF Download: 666

Opinion

Cell Energy: A New Hypothesis in Decoding Cancer Evolution

Hassan Akbari 1,2, Farzad Taghizadeh-Hesary 3* ORCID logo, Yuji Heike 4, Moslem Bahadori 5

1 Department of Pathology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2 Traditional Medicine School, Tehran University of Medical Sciences, Tehran, Iran
3 Department of Radiation-oncology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4 Dean, Collaborative Research Laboratory, St Luke’s International Hospital, Tokyo, Japan
5 Professor emeritus, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
*Corresponding Author: Email: Farzadth89@gmail.com

Abstract

The present study deviates from previous approaches as it focuses on the concept of energy to illuminate cancer-related issues. Energy is a prerequisite for any function; cellular function is no exception, and thus, reduced energy in human cells can impair their performance. This hypothesis provides a novel view of cancer formation. It shows that a normal cell transforms into its cancerous counterpart in response to cellular adenosine triphosphate (ATP) depletion. Moreover, it presents a new definition for the origin of cancer stem cells and how they can regenerate cancer. This article regards a distinct aspect of cancer that helps to differentiate various phases of its progression and shed light on some of the uncharted zones of its pathway for the first time that needs further confirmation by empirical studies.

Cite this article as: Akbari H, Taghizadeh-Hesary F, Heike Y, Bahadori M. Cell energy: a new hypothesis in decoding cancer evolution. Arch Iran Med. 2019;22(12):733–735.
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Submitted: 14 Sep 2019
Accepted: 07 Oct 2019
ePublished: 01 Dec 2019
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