Arch Iran Med. 2022;25(3): 166-170.
doi: 10.34172/aim.2022.28
  Abstract View: 713
  PDF Download: 376

Original Article

Rates and Reasons of Laboratory Sample Rejection due to Pre-analytical Errors in Clinical Settings

Elham Jafari 1* ORCID logo, Reza Malekpour Afshar 1 ORCID logo, Razieh Aminzade 1

1 Pathology and Stem Cells Research Center, Department of Pathology, Kerman University of Medical Sciences, Kerman, Iran
*Corresponding Author: *Corresponding Author: Elham Jafari, MD, APCP; Pathology and Stem Cells Research Center, Department of Pathology, Kerman University of Medical Sciences, Kerman, Iran. Tel:+98-+98-913-3997648; Fax:+98-34-33257112; Email: , Email: ejfarda@yahoo.com


Background: Laboratory analysis errors in procedure or interpretation may be seen during the process of completing physician test orders. They may also result in rejection of the requests due to some applicability reasons. Hence, this study was carried out to determine the rate and reasons for such rejections in clinical settings.

Methods: This cross-sectional comparative study was performed on 104008 laboratory tests in a one-year period in terms of the percentage and type of errors that occurred in Shahid Bahonar Hospital in Kerman, Iran, in 2018. The types of studied errors included hemolysis, sample clotting, insufficient sample size, and mistakes in labels or absence of labels on the sample.

Results: In this study, 104008 laboratory tests were performed, with 2299 (2.21%) sample rejections, 456 (32.31%) complete blood count (CBC) sample clotting; 417 (29.38 %) hemolysis; and 150 (17.47 %) inadequate sample volume as the majority of errors. There was no statistically significant relationship between pre-analysis errors and clinical aspects (P=0.124).

Conclusion: According to the results, it may be concluded that considering the high prevalence of laboratory errors in comparison with the majority of other studies, continuous training courses and determination of the causes of these errors are crucial to attaining better function and basic knowledge.

Cite this article as: Jafari E, Malekpour Afshar R, Aminzade R. Rates and reasons of laboratory sample rejection due to pre-analytical errors in clinical settings. Arch Iran Med. 2022;25(3):166-170. doi: 10.34172/aim.2022.28
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Submitted: 28 Oct 2020
Revision: 29 May 2021
Accepted: 16 Jun 2021
ePublished: 01 Mar 2022
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