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Arch Iran Med. 2020;23(11): 782-786.
doi: 10.34172/aim.2020.104
  Abstract View: 127
  PDF Download: 79

COVID-19

Original Article

COVID-19 and Digestive System in Children: A Retrospective Study

Mohammadreza Esmaeili Dooki 1 ORCID logo, Sanaz Mehrabani 1* ORCID logo, Hadi Sorkhi 1, Maryam Nikpour 1, Mohamadreza Tabatabaie 2, Mohsen Mohammadi 1, Masood Kiani 1

1 Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R. Iran
2 Clinical Research Development Center, Amirkola Children’s Hospital, Babol University of Medical Sciences, Babol, I.R. Iran
*Corresponding Author: Sanaz Meherabani, MD; Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R. Iran. Address: Non-Communicable Pediatric Disease Research Center, N 19, Amirkola Children’s Hospital, Babol, Mazandaran 47317- 41151, IR Iran. Iran. Zip Code: 47176-47745; Tell-Fax: +98 11 32346963; Email: mehrabanisanaz@yahoo.com

Abstract

Background: The aim of this study was to identify gastrointestinal (GI) and liver injury presentations in children admitted with COVID-19 infection.

Methods: In this retrospective study, we studied all children with suspected symptoms of COVID-19, referred to Amirkola Children’s Hospital. Clinical manifestations of the digestive and respiratory systems and liver function tests were evaluated for all cases.

Results: Eighteen children were studied. The most common clinical symptoms were fever, anorexia, weakness, nausea and vomiting, cough, diarrhea, and abdominal pain, respectively. Also, 5/18 (27.8%) and 7/18 (38.9%) of cases had abnormally high alanine aminotransferase (ALT), aspartate aminotransferase (AST), respectively. Additionally, in icteric cases, direct bilirubin was raised. There was no significant relationship between pulmonary lesions and abnormal excess in ALT (P = 0.59) and AST (P = 0.62).

Conclusion: The findings showed that there were no severe clinical GI symptoms in children with COVID-19 infection. Besides, children with increased liver enzymes did not have more respiratory involvement than those without a rise in liver enzymes.

Keywords: COVID – 19, Gastrointestinal tract, Liver, Pediatric
Cite this article as: Esmaeili Dooki M, Meherabani S, Sorkhi H, Nikpour M, Tabatabaie M, Mohammadi M, et al. COVID-19 and digestive system in children: a retrospective study. Arch Iran Med. 2020;23(11):782–786. doi: 10.34172/aim.2020.104.
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Submitted: 07 Jun 2020
Accepted: 06 Sep 2020
ePublished: 01 Nov 2020
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