Logo-aim
Arch Iran Med. 2020;23(11): 794-800.
doi: 10.34172/aim.2020.106
  Abstract View: 113
  PDF Download: 46

COVID-19

Review

A Review on Applicable and Available Paraclinical Methods for Diagnosis of Coronavirus Disease-19

Mohammad Rafiee 1 ORCID logo, Farahnaz Parsaei 2, Sajjad Rahimi Pordanjani 3, Vahid Amiri 1, Siamak Sabour 4* ORCID logo

1 Department of Hematology and Blood Banking, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2 Student’s Research Committee, Shahrekord University of Medical Sciences, Shahrekord, Iran
3 Research Center for Health Sciences and Technologies, School of Health, Semnan University of Medical Sciences, Semnan, Iran
4 Department of Clinical Epidemiology, School of Public Health and Safety, Safety Promotion and Injury Prevention Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
*Corresponding Author: Siamak Sabour, MD, PhD; Department of Clinical Epidemiology, School of Public Health and Safety, Safety Promotion and Injury Prevention Research Center, Shahid Beheshti University of Medical Sciences, Chamran Highway, Velenjak, Daneshjoo Blvd, Tehran, 198353-5511, Iran. Email: s.sabour@gmail.com

Abstract

Background: The recent outbreak by a novel coronavirus originated from Wuhan, China in 2019, and is progressively spreading to other countries. Timely diagnosis of the coronavirus disease 2019 (COVID-19) improves the survival of the patients and also prevents the transmission of the infection. In this study, we reviewed the applicable and available methods for the diagnosis of COVID-19.

Methods: For the review, we systematically searched Web of Science, PubMed, and Iranian articles that were published about COVID-19 diagnostic methods with a combination of the key terms: laboratory, radiological, tests, coronavirus.

Results: Although the current gold standard diagnostic test for this virus is real-time reverse-transcriptase polymerase chain reaction (RT-PCR), the occasional false-negative and the low sensitivity of the test should not be underestimated. A chest computed tomography (CT) scan is another diagnostic test for COVID-19, with higher sensitivity but low specificity. A combination of sensitive RT-PCR with a chest CT scan together with the clinical features are highly recommended for the proper diagnosis. Notably, there are some other sensitive and low-cost tests for evaluation of COVID-19 infection, but their validation should be approved.

Conclusion: Since early and accurate diagnosis of the viral disease could improve the survival rate of the patients, and halt the transmission chain, it is not surprising that tremendous attempts should be made to reduce the limitations of the tests leading to the false-negative results and to find a rapid test for the diagnosis of COVID-19.

Keywords: 2019-nCov, Chest CT scan, COVID-19, Real-time RT-PCR
Cite this article as: Rafiee M, Parsaei F, Rahimi Pordanjani S, Amiri V, Sabour S. A review on applicable and available paraclinical methods for diagnosis of coronavirus disease-19. Arch Iran Med. 2020;23(11):794–800. doi: 10.34172/aim.2020.106.
First Name
 
Last Name
 
Email Address
 
Comments
 
Security code


Abstract View: 113

Your browser does not support the canvas element.


PDF Download: 46

Your browser does not support the canvas element.

Submitted: 31 Mar 2020
Accepted: 06 Sep 2020
ePublished: 01 Nov 2020
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)